Dairy | CAVL Autogenous Vaccines

Custom Vaccines Commercial, broad-application type vaccines may not be specific enough to give the level of protection you and your clients need. CAVL can work with veterinarians to collect samples, isolate the disease causing bacteria, and jointly develop a custom-made, strain-specific vaccine.

Visit the CAVL website.

Depending on your needs CAVL can make a vaccine for a specific client or a vaccine specific for your practice.

• CAVL Custom Vaccines target the specific diseases affecting your herd
• CAVL custom vaccines are designed to pinpoint the specific bacterial pathogens affecting a herd. Pathogenic bacteria frequently express different surface antigens and exhibit diverse antibiotic resistance patterns.
• CAVL can work with you to select the most resistant bacteria for your custom-made vaccine. For over 25 years, CAVL has worked jointly with veterinarians and their clients with the following bacteria:
  • Pasteurella multocida
  • Haemophilus somnus
  • Moraxella bovis
  • Pasteurella haemolytica
  • Salmonella species
  • Escherichia coli
• CAVL recommends an initial vaccination followed by a booster vaccination in 10 to 14 days. Each custom-made vaccine can be produced in a four-week period, from the time of bacterial isolation until the finished product is available for shipment. Our technical and professional support staff is available to service client needs and answer questions concerning your custom-made vaccine.
• We’ll help you track and address disease changes which might affect your herd.
• CAVL monitors the epidemiology of numerous organisms of importance to veterinarians and producers. Shifts in pathogens or antibiotic resistance can have a profound effect on animal health decisions.
• A summary of bacteria isolated in the CAVL diagnostic laboratory, as well as a summary of antibiotic sensitivity profiles found in an area, can be sent to you on a quarterly basis. This summary will allow you to compare the bacterial isolates and sensitivity patterns from an area with the overall results obtained by the CAVL diagnostic lab from others in the vicinity. This can provide additional information to keep you updated about newly emerging pathogens.

  It is important to remember that newly isolated pathogens can be added to a custom-made vaccine any time that a new production run is started. As a result, CAVL can work with veterinarians to add or delete isolates as the epidemiologic profile of a herd dictates. The process of periodic sampling allows CAVL to adjust to changing needs.

  This free service is provided to CAVL vaccine clients. Details on other CAVL program specials will also be included in the periodic summaries so be sure to watch for them.

  All CAVL custom-made vaccines are produced in accordance with USDA guidelines and meet all safety and sterility requirements. To find out more about how CAVL’s Custom Vaccines can benefit your operation, call toll-free 1-800-262-2486.

COLLECTION & TRANSPORTATION

Collection and transportation of specimens

When submitting samples for isolation we suggest the following guidelines be used:

• Pasteurella haemolytica and multocida (in order of most to least preferred sample:) Lung, mediastinal lymph nodes, tracheal washings, laryngeal swabs, nasal swabs.
• Haemophilus somnus (in order of most to least preferred sample:)
  Lung, brain, mediastinal lymph nodes, joint fluid, tracheal washings, laryngeal swabs, nasal swabs.
• Salmonella (in order of most to least preferred sample:) Gall bladder, bile, small intestine, mesenteric lymph nodes, liver, feces, rectal swabs.

Nasal and Rectal Swabs, tissue Samples:

1. Remove sterile swab from plastic tube. Do not touch swab to anything so as not to contaminate it.
2. Wipe inside the nasal cavity with a paper towel. Insert sterile swab as far into the nasal cavity as possible, once inserted be sure to rub on the inside of the nostril and rotate. Be careful not to touch outside of nose when entering or withdrawing swab. For rectal swab lift tail and insert swab into rectum and rotate. Again be careful removing swab.
3. Insert swab into plastic tube pushing down into media. When using culturettes, crush ampule between thumb and finger and push swab into media.
4. For tissue samples, collect about a 3-inch cube of lung, liver, etc. and a 4-inch piece of intestine. Place each tissue in a separate whirl-pak bag. Collect the area of tissue that exhibits gross lesions.
5. Label tube or bag with as much information as possible: Lot number, pen number, tag number, type of swab (nasal or rectal).
6. Keep samples cool. Ship as soon as possible.

Transportation of Samples

1. Pack in cardboard box or Styrofoam cooler.
2. Enclose frozen polar paks to keep samples cool, even in cool weather. Do not place ice paks directly against samples.
3. Protect samples with newspaper or some other form of packing material.
4. Ship to the laboratory overnight or 2nd day. Our couriers of choice are Fed-Ex, Airborne, Bus, UPS. If you are shipping after Wednesday, please check for Saturday delivery. Fed-Ex and UPS deliver to our area on Saturday until noon.
5. It is best to give us a call when sending samples so we will be expecting the delivery.
    

 

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